On-substrate derivatization for detection of highly volatile G-series chemical warfare agents via paper spray mass spectrometry.
Phillip M MachElizabeth S DhummakuptDaniel O CarmanyEthan M McBrideMichael W BuschPaul S DemondGabrielle M RizzoDonna E HollinsheadTrevor G GlarosPublished in: Rapid communications in mass spectrometry : RCM (2018)
Derivatization of paper spray substrates was shown to greatly increase the time for analysis of CWAs. This technique, combined with the vapor phase capture stage outlined previously, allows for rapid, quantitative CWA detection by paper spray ionization with little or no sample preparation.
Keyphrases
- gas chromatography
- mass spectrometry
- loop mediated isothermal amplification
- liquid chromatography
- high performance liquid chromatography
- tandem mass spectrometry
- gas chromatography mass spectrometry
- high resolution mass spectrometry
- ms ms
- liquid chromatography tandem mass spectrometry
- high resolution
- real time pcr
- ultra high performance liquid chromatography
- solid phase extraction
- label free
- simultaneous determination
- sensitive detection
- molecularly imprinted
- capillary electrophoresis