Children at Familial High risk of Schizophrenia and Bipolar Disorder Exhibit Altered Connectivity Patterns During Pre-attentive Processing of an Auditory Prediction Error.

Kit Melissa LarsenKathrine Skak MadsenAnna Hester Ver Loren van ThemaatAnne Amalie Elgaard ThorupKerstin Jessica PlessenOle MorsMerete NordentoftHartwig Roman Siebner

Published in: Schizophrenia bulletin (2023)

We provide novel evidence that connectivity underlying MMN responses in children at FHR for schizophrenia and bipolar disorder is altered at the age of 11-12, echoing findings that have been found in individuals with manifest schizophrenia.

Keyphrases

bipolar disorder
major depressive disorder
young adults
resting state
functional connectivity
white matter
working memory
early onset
multiple sclerosis