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In Vivo Antioxidant Activity of Different Fractions of Indigofera Barberi Against Paracetamol-induced Toxicity in Rats.

Shaik AminabeeAtmakuri Lakshmana RaoMaram Chinna Eswaraiah
Published in: Turkish journal of pharmaceutical sciences (2020)
From the results, fraction D of Indigofera barberi at a dose of 100 mg/kg, p.o., improved the SOD, catalase and peroxidase activities, and glutathione levels significantly. Based on this study, we can conclude that fraction D of Indigofera barberi possesses in vivo antioxidant activity and can be employed in protecting tissue from oxidative stress.
Keyphrases
  • oxidative stress
  • diabetic rats
  • high glucose
  • dna damage
  • hydrogen peroxide
  • ischemia reperfusion injury
  • drug induced
  • nitric oxide
  • anti inflammatory drugs
  • endoplasmic reticulum stress