Irreversible electroporation augments β-glucan induced trained innate immunity for the treatment of pancreatic ductal adenocarcinoma.
Matthew R WoesteRejeena ShresthaAnne E GellerShu LiDiego Montoya-DurangoChuanlin DingXiaoling HuHong LiAaron PuckettRobert A MitchellTraci HayatMin TanYan LiKelly M McMastersRobert C G MartinJun YanPublished in: Journal for immunotherapy of cancer (2023)
These data highlight a relevant and novel application of trained immunity within the setting of surgical ablation that may stand to benefit patients with PC.