First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers.

Lisa M PitchfordJohn A RathmacherJohn C FullerJ Scott DanielsRyan D MorrisonWendall S AkersNaji N AbumradVenkataraman AmarnathPatricia M CurreyL Jackson RobertsJohn A OatesOlivier Boutaud

Published in: BMC pharmacology & toxicology (2019)

This study is registered at ClinicalTrials.gov (NCT03176940).

Keyphrases

endothelial cells
open label
study protocol