Prevalence/incidence of atrial fibrillation based on integrated medical/pharmacy claims, and association with co-morbidity profiles/multi-morbidity in a large US adult cohort.

Continued reliance only on outpatient and inpatient claims greatly underestimates AF prevalence and incidence in the general population by over 100%. Multi-morbidity is common amongst AF patients, affecting approximately 1 in 10 patients. AF patients with four or more co-morbidities captured 20%-40% of the AF cohorts depending on age groups and prevalent or incident cases.