The m6A methylation regulates gonadal sex differentiation in chicken embryo.

Jianbo LiXiuan ZhangXiqiong WangCongjiao SunJiangxia ZhengJunying LiGuoqiang YiNing Yang

Published in: Journal of animal science and biotechnology (2022)

This work provided a comprehensive m6A methylation profile of chicken embryonic gonads and revealed YTHDC2 as a key regulator responsible for sex differentiation. Our results contribute to a better understanding of epigenetic factors involved in chicken sex determination and differentiation and to promoting the future development of sex manipulation in poultry industry.

Keyphrases

dna methylation
gene expression
genome wide
current status
solid phase extraction
molecularly imprinted
pregnancy outcomes