Unravelling how in vitro capacitation alters ram sperm chromatin before and after cryopreservation.

Patricia Peris-FrauManuel Álvarez-RodriguezAlicia Martín-MaestroMaría Iniesta-CuerdaIrene Sánchez-AjofrínDaniela Alejandra Medina-ChávezJosé Julián GardeMargarita VillarHeriberto Rodríguez-MartínezMaría Del Rocío Fernández-Santos

Published in: Andrology (2020)

Our results suggest that sperm chromatin condensation decreased progressively during in vitro capacitation of ram spermatozoa, while sperm DNA integrity remained intact. Such changes in chromatin condensation appeared faster after sperm cryopreservation.

Keyphrases

dna damage
gene expression
transcription factor
genome wide
cell free
circulating tumor
circulating tumor cells