The IL-4 rs2070874 polymorphism may be associated with the severity of recurrent viral-induced wheeze.
Flore AmatMalek LouhaMarta BenetTamazoust GuiddirMélisande Bourgoin-HeckPhilippe Saint-PierreColombe Paluel-MarmontCécile FontaineNathalie LambertRémy CoudercJuan-Ramon GonzalezJocelyne JustPublished in: Pediatric pulmonology (2017)
Association between the TT-genotype of IL-4 rs2070874 polymorphism and a severe phenotype of viral-induced wheeze further underlines the role IL-4 plays in the inflammation pathway leading to viral respiratory infections.