On-treatment HBV DNA dynamics predict virological breakthrough in entecavir-treated HBeAg-positive chronic hepatitis B.

Yi-Jie HuangChi-Sen ChangYen-Chun PengHong-Zen YehSheng-Shun Yang

Published in: PloS one (2017)

Our results demonstrated that on-treatment HBV DNA could probably predict VBT in ETV-treated HBeAg-positive chronic hepatitis B patients. Failure to achieve HBeAg seroclearance was associated with VBT in ETV-treated HBeAg-positive CHB patients. HBV DNA >100IU/mL at 48 weeks is potentially a predictor for VBT.

Keyphrases

hepatitis b virus
newly diagnosed
end stage renal disease
liver failure
ejection fraction
chronic kidney disease
circulating tumor
single molecule
cell free
prognostic factors
peritoneal dialysis
patient reported outcomes
hiv infected
antiretroviral therapy
replacement therapy
gestational age