Evaluation of bone turnover after bisphosphonate withdrawal and its influence on implant osseointegration: an in vivo study in rats.

Fausto FrizzeraMario Henrique Arruda VerzolaRafael Scaf de MolonGuilherme Jose Pimentel Lopes de OliveiraGabriela GiroLuis Carlos SpolidorioRosa Maria Rodrigues PereiraSotirios TetradisJoni Augusto CirelliSilvana Regina Peres Orrico

Published in: Clinical oral investigations (2018)

The severe suppression of bone turnover caused by the prolonged use of ALD may alter the capacity of bone tissue to integrate with the implant threads impairing the osseointegration process.

Keyphrases

bone mineral density
soft tissue
postmenopausal women
body composition
bone loss
bone regeneration
drug induced