Primary squamous cell carcinoma of the testis: a rare presentation.
Aqsa ZahoorRajiv SwamyAndrew GogbashianAnand SharmaPublished in: BMJ case reports (2022)
A man in his mid-70s presented with a lump in his left testicle. He had previously been treated for prostate cancer with radical radiotherapy. He was on treatment for hypertension and type 2 diabetes. An ultrasound of the testes demonstrated a solid intratesticular mass for which he underwent left orchidectomy. Histology from the orchidectomy was moderately differentiated squamous cell carcinoma (SCC), positive for cytokeratin (CK) 5/6 and p63. A positron emission tomogram (PET) scan was clear of any metastatic disease. His surveillance CT, done at 12 months, revealed mediastinal, abdominal and hilar adenopathy. Biopsy of hilar lymph nodes showed SCC and this was treated with platinum-based chemotherapy. Unfortunately, the patient died after 18 months. To our knowledge, this is the first reported case of metastatic SCC of testes with extensive spread and with platinum-refractory disease.
Keyphrases
- squamous cell carcinoma
- locally advanced
- lymph node
- prostate cancer
- computed tomography
- type diabetes
- ultrasound guided
- small cell lung cancer
- neoadjuvant chemotherapy
- lymph node metastasis
- case report
- blood pressure
- positron emission tomography
- healthcare
- magnetic resonance imaging
- early stage
- rectal cancer
- radical prostatectomy
- insulin resistance
- radiation therapy
- image quality
- metabolic syndrome
- glycemic control
- radiation induced
- fine needle aspiration
- pet imaging
- weight loss
- pet ct
- smoking cessation