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Transcriptional Repression by FoxM1 Suppresses Tumor Differentiation and Promotes Metastasis of Breast Cancer.

Dragana KopanjaVaibhav ChandEilidh O'BrienNishit K MukhopadhyayMaria Paula ZappiaAbul Bashar Mir Md Khademul IslamMaxim V FrolovBradley J MerrillPradip Raychaudhuri
Published in: Cancer research (2022)
This work provides new insights into how the interaction between FoxM1 and Rb facilitates the evolution of metastatic breast cancer cells by altering the transcriptome.
Keyphrases
  • breast cancer cells
  • gene expression
  • squamous cell carcinoma
  • small cell lung cancer
  • rna seq
  • single cell
  • signaling pathway
  • transcription factor
  • genome wide
  • young adults
  • oxidative stress
  • heat shock protein