Modulation of the functional connectome in major depressive disorder by ketamine therapy.

Ashish K SahibJoana R LoureiroMegha VasavadaCole AndersonAntoni KubickiBenjamin WadeShantanu H JoshiRoger P WoodsEliza CongdonRandall EspinozaKatherine L Narr

Published in: Psychological medicine (2020)

Results support that ketamine treatment leads to neurofunctional plasticity between distinct neural networks that are shown as disrupted in MDD patients. Cortico-striatal-cerebellar loops that encompass the SN could be a potential biomarker for ketamine treatment.

Keyphrases

major depressive disorder
bipolar disorder
neural network
end stage renal disease
pain management
ejection fraction
chronic kidney disease
newly diagnosed
stem cells
prognostic factors
functional connectivity
cell therapy