Association of ESR1 germline variants with TP53 somatic variants in breast tumors in a genome-wide study.
Nijole P TjaderAbigail J BeerJohnny RamroopMei Chee TaiJie PingTanish GandhiCara DauchSusan L NeuhausenElad ZivNereida SoteloShreya GhanekarOwen MeadowsMonica ParedesJessica L GillespieAmber M AeiltsHeather HampelQuan LongGuochong JiaQiang HuLei WeiSong LiuChristine B AmbrosoneJulie R PalmerJohn D CarptenSong YaoPatrick StevensWeang Kee HoJia Wern PanPaola FaddaDezheng HuoSoo-Hwang TeoJoseph Paul McElroyAmanda Ewart TolandPublished in: medRxiv : the preprint server for health sciences (2023)
mutations and GOF mutations. Larger multi-ancestry studies are needed to confirm these findings and determine if these variants contribute to ancestry-specific differences in mutation frequency.