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Red cells manufactured from lipaemic whole blood donations: Do they have higher haemolysis?

Kelly M WinterRachel G WebbDenese C Marks
Published in: Vox sanguinis (2022)
There was no significant difference in haemolysis in RBC manufactured from lipaemic and non-lipaemic whole blood donations when stored in SAGM; however, the proportion of RBC from lipaemic donations with higher haemolysis was greater than in the controls. There was a weak correlation between red cell haemolysis and plasma triglycerides. Therefore, RBCs derived from lipaemic donations are suitable for blood bank inventories.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • single cell
  • red blood cell
  • room temperature
  • cell death
  • signaling pathway
  • endoplasmic reticulum stress
  • pi k akt