The effects of combustible cigarettes and electronic nicotine delivery systems on immune cell-driven inflammation and mucosal healing in ulcerative colitis.
Nikolina KastratovicVladimir MarkovicAleksandar ArsenijevicAna VolarevicNatasa ZdravkovicMarija ZdravkovicMarija Svetislav BrankovićTijana GmizicCarl Randall HarrellVladimir JakovljevicValentin DjonovVladislav VolarevicPublished in: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco (2024)
This is the first study that compared the effects of CCs and ENDS on immune cells of patients suffering from ulcerative colitis, providing new information about molecular and cellular mechanisms which were responsible for ENDS and CCs-dependent modulation of immune cell-driven colon injury and inflammation. Obtained results showed that both ENDS and CCs had capacity to attenuate detrimental immune response, enhanced healing and ameliorated recovery of injured intestines.