Gut microbial-derived butyrate is inversely associated with IgE responses to allergens in childhood asthma.
Chih-Yung ChiuMei-Ling ChengMeng-Han ChiangYu-Lun KuoMing-Han TsaiChun-Che ChiuGigin LinPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2019)
A reduced fecal butyrate is associated with increased mite-specific IgE levels and the risk of asthma in early childhood. Fecal β-alanine could be a specific biomarker connecting the metabolic dysbiosis of gut microbiota, Clostridium and Escherichia spp., in childhood asthma.