Maternal germline factors associated with aneuploid pregnancy loss: a systematic review.
Ursula BlythLaurentiu CraciunasGavin HudsonMeenakshi ChoudharyPublished in: Human reproduction update (2022)
Identifying maternal genetic factors associated with an increased risk of aneuploidy will expand our understanding of cell division, non-disjunction and miscarriage secondary to embryo aneuploidy. The candidate germline factors identified may be incorporated in a screening panel for women suffering miscarriage of aneuploidy aetiology to facilitate counselling for subsequent pregnancies.
Keyphrases
- pregnancy outcomes
- pregnant women
- dna repair
- single cell
- cell therapy
- genome wide
- smoking cessation
- type diabetes
- dna damage
- dna methylation
- polycystic ovary syndrome
- metabolic syndrome
- hepatitis c virus
- oxidative stress
- adipose tissue
- skeletal muscle
- insulin resistance
- human immunodeficiency virus
- antiretroviral therapy