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Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years.

Kevin L WinthropYoshiya TanakaTsutomu TakeuchiAlan KivitzFranziska MatzkiesMark C GenoveseDeyuan JiangKun ChenBeatrix BartokAngelika JahreisRobin BesuyenGerd-Rüdiger R BurmesterJacques-Eric Gottenberg
Published in: Annals of the rheumatic diseases (2021)
Over a median of 1.6 and maximum of 5.6 years of exposure, safety/tolerability of FIL200 and FIL100 were similar, with a lower incidence of infections with FIL200 among the long-term, as-treated dataset.
Keyphrases
  • rheumatoid arthritis
  • risk factors
  • open label
  • disease activity
  • clinical trial
  • combination therapy
  • study protocol
  • replacement therapy
  • placebo controlled