Associations of air pollution with peripheral inflammation and cardiac autonomic physiology in children.
Anna M ParenteauNicholas V AlenJennifer LaAlison T LuckDevin J TeichrowEnya M DaangAdam T NissenLillyBelle K DeerCamelia E HostinarPublished in: New directions for child and adolescent development (2022)
Climate change-related disasters have drawn increased attention to the impact of air pollution on health. 122 children ages 9-11 years old, M(SD) = 9.91(.56), participated. Levels of particulate matter (PM2.5) near participants' homes were obtained from the Environmental Protection Agency. Cytokines were assayed from 100 child serum samples: IL-6, IL-8, IL-10, and TNFα. Autonomic physiology was indexed by pre-ejection period (PEP), respiratory sinus arrhythmia (RSA), cardiac autonomic regulation (CAR), and cardiac autonomic balance (CAB). IL-6 was positively related to daily PM2.5 (r = .26, p = .009). IL-8 was negatively associated with monthly PM2.5 (r = -.23, p = .02). PEP was positively related to daily (r = .29, p = .001) and monthly PM2.5 (r = .18, p = .044). CAR was negatively associated with daily PM2.5 (r = -.29, p = .001). IL-10, TNFα, RSA, and CAB were not associated with PM2.5. Air pollution may increase risk of inflammation in children.
Keyphrases
- air pollution
- particulate matter
- lung function
- climate change
- heart rate variability
- heart rate
- young adults
- physical activity
- rheumatoid arthritis
- left ventricular
- mental health
- oxidative stress
- healthcare
- public health
- heavy metals
- heart failure
- working memory
- cystic fibrosis
- atrial fibrillation
- social media
- catheter ablation