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Differentiation syndrome in patients with acute promyelocytic leukemia.

Nusiba H ElaminFarah RashidMuhammad S AfanaHonar CherifMohamad A Yassin
Published in: Clinical case reports (2023)
A 48-year-old male diagnosed with acute promyelocytic leukemia (APL) started on all-trans-retinoic acid and arsenic trioxide, developed typical symptoms of differentiation syndrome, and improved dramatically on steroids. Hence, any APL patient started on chemotherapy, needs to be monitored closely for developing differentiation syndrome and to start steroid upon suspicion.
Keyphrases
  • case report
  • acute myeloid leukemia
  • bone marrow
  • liver failure
  • drinking water
  • squamous cell carcinoma
  • sleep quality
  • acute respiratory distress syndrome
  • mechanical ventilation