The Role of Vildagliptin in Treating Hypertension Through Modulating Serum VEGF in Diabetic Hypertensive Patients.

Abdel Rahman El-NaggarDalia K ZaafarMohammed ElyamanySoha HassaninAtef BassyouniHekma Abdel-Latif

Published in: Journal of cardiovascular pharmacology and therapeutics (2019)

Vildagliptin showed a promising action through its blood pressure-regulating effect via modulating VEGF levels and improving physiological angiogenesis and vasculature, in addition to improving the lipid profile of patients, while metformin was better in reducing body weight.

Keyphrases

blood pressure
hypertensive patients
body weight
vascular endothelial growth factor
endothelial cells
end stage renal disease
chronic kidney disease
heart rate
ejection fraction
newly diagnosed
prognostic factors
wound healing
peritoneal dialysis
adipose tissue
skeletal muscle
weight loss