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Acute phenthoate self-poisoning: a prospective case series.

Lekaashree RambabuFahim MohamedJeevan DhanarisiIndika GawarammanaJacques E RaubenheimerLorraine MackenzieMichael S RobertsNicholas Alan BuckleyMichael Eddleston
Published in: Clinical toxicology (Philadelphia, Pa.) (2021)
Phenthoate self-poisoning has a 6.5% case fatality rate. Most patients who experience respiratory failure undergo early intubation; most deaths occurred among those patients who were intubated less than 24 h after ingestion. There was a non-sustained increase in cholinesterase activity with pralidoxime, but further studies are required to analyse the extent to which oximes are clinically effective in phenthoate self-poisoning.
Keyphrases
  • respiratory failure
  • extracorporeal membrane oxygenation
  • mechanical ventilation
  • cardiac arrest
  • acute respiratory distress syndrome
  • liver failure