The impact of short term Antiretroviral Therapy (ART) interruptions on longer term maternal health outcomes-A randomized clinical trial.
Patience AtuhaireSean S BrummelBlandina Theophil MmbagaKonstantia AngelidouLee FairlieAvy ViolariGerhard TheronCornelius MukuzungaSajeeda MawlanaMwangelwa Mubiana-MbeweMegeshinee NaidooBonus MakananiPatricia MandimaTeacler NematadziraNishi SuryavanshiTapiwa MbengeranwaAmy LoftisMichael BasarKatie McCarthyJudith S CurrierMary Glenn Fowlernull nullPublished in: PloS one (2020)
The incidence of AIDS and/or death was low in pregnant/postpartum HIV+ women with highCD4 cell counts for all comparison arms. This provides some reassurance that there were limited consequences for short term ART interruption in this group of asymptomatic HIV+ women during up to 4 years of follow up; and underscores that even short term ART exposure postpartum may reduce the risk of WHO grade 2-3 disease progression.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- pregnancy outcomes
- pregnant women
- risk factors
- polycystic ovary syndrome
- single cell
- cell therapy
- stem cells
- type diabetes
- peripheral blood
- hepatitis c virus
- adipose tissue
- gestational age
- south africa
- weight loss
- body mass index
- insulin resistance