Radiation-induced changes in the microstructure of epithelial cells of the oral mucosa: A comparative light and electron microscopic study.

Pekka J AsikainenHannah DekkerEllinoora SirviöJopi MikkonenEngelbert A J M SchultenElisabeth BloemenaArto KoistinenChris M Ten BruggenkateArja M Kullaa

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2017)

Scanning electron microscopy, in contrast to light microscopy, appears to be a useful tool to reveal the condition of superficial oral mucosal cells. In respect of the possible pathogenesis of osteoradionecrosis, the radiation-induced damage of the microplicae and its influence on the mucosal salivary pellicle is discussed.

Keyphrases

electron microscopy
radiation induced
radiation therapy
induced apoptosis
ulcerative colitis
high resolution
magnetic resonance
oxidative stress
cell cycle arrest
white matter
high throughput
single molecule
mass spectrometry
gene expression
genome wide
single cell
cell proliferation
cell death
label free