Prognostic Relevance of Type 2 Diabetes and Metformin Treatment in Head and Neck Melanoma: Results from a Population-Based Cohort Study.

Steffen SpoerlMichael GerkenSusanne SchimnitzJuergen TaxisRené FischerSophia R LindnerTobias EttlNils LudwigSilvia SpoerlTorsten E ReichertGerrit Spanier

Published in: Current oncology (Toronto, Ont.) (2022)

This study emphasizes that DM2 is a relevant comorbid condition in HNM patients, impairing patient survival. Metformin intake was associated with a favorable outcome in HNM patients, providing possible therapeutic implications for future adjuvant treatment regimes.

Keyphrases

type diabetes
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
cardiovascular disease
early stage
patient reported outcomes
physical activity
insulin resistance
free survival