Selecting esophageal cancer patients for lymphadenectomy after neoadjuvant chemoradiotherapy: a modeling study.

Mirre Scholte Didi Jjm de GouwBastiaan R KlarenbeekJanneke Pc GruttersCamiel RosmanMaroeska M Rovers

Published in: BMJ surgery, interventions, & health technologies (2020)

The reduction in LND-related complications that is accomplished by selecting patients for LND based on restaging results after nCRT seems not to outweigh a QALY loss in the long-term due to residual LN metastases. Despite the short-term advantages of selective LND, this strategy can only match long-term QALYs of standard LND when its success rate equals the success rate of standard LND.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
lymph node
rectal cancer
early stage
risk factors
patient reported outcomes
radiation therapy
patient reported
lymph node metastasis
neoadjuvant chemotherapy