Performance evaluation of three rapid screening assays for detection of antibodies to hepatitis C virus in Cameroon.

Clavel Landry Kouam FondjoPaul Alain Tagnouokam NgoupoLaure NgonoJean-Christophe PlantierRichard Njouom

Published in: BMC research notes (2018)

Overall, 200 plasma samples were used. Sensibility and specificity of these RDTs range from 71 to 99 and 78 to 100% respectively. Multisure scored a sensitivity at 99% (95% CI 97-100%) and First Response reached a specificity at 90% (95% CI 85-94.9%). Further studies should be conducted to establish an algorithm using these RTDs for the detection of HCV infection in Cameroon.

Keyphrases

hepatitis c virus
loop mediated isothermal amplification
human immunodeficiency virus
label free
real time pcr
machine learning
sensitive detection
deep learning
high throughput
neural network