Single-nucleotide polymorphism in chronic rhinosinusitis: A systematic review.

Antonino ManiaciMusso NicolòJérôme René LechienMerlino FedericoViglianisi ChiaraStracquadanio StefanoSantagati MariaCocuzza SalvatoreBonanno AntonioChristian Calvo-HenríquezStefani StefaniaIgnazio La Mantia

Published in: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (2021)

Our systematic review revealed the major SNPs significantly associated with chronic rhinosinusitis and the specific pathways involved. Given the presence of different extraction methods and samples sequencing, further studies with larger courts are necessary to identify significative single-nucleotide polymorphisms.

Keyphrases

chronic rhinosinusitis
systematic review
single cell
meta analyses
genome wide
gene expression
genome wide association