Evaluation of the clinical utility of maximum intensity projections of 3D contrast-enhanced, T1-weighted imaging for the detection of brain metastases.
Nicolin HaincChristian FederauAnthony TyndallAndreas MittermeierAndrea BinkChristoph StippichTilman SchubertPublished in: Cancer reports (Hoboken, N.J.) (2020)
About 22.5 61.2 s/study and 43.8 ± 159.9 s/study were saved using 5 and 10 mm MIPs, respectively. Combined average sensitivity was 92.0% for 5 mm MIPs and 86.3% for 10 mm MIPs compared to standard 1 mm axial slices, with an average rate of 0.98 and 0.57 false positives per study, respectively CONCLUSION: While 5 mm and 10 mm T1ce MP-RAGE MIPs showed a clinical benefit in reducing reading times for evaluation of brain metastases, they should be used in conjunction with standard 1 mm images for best sensitivity and specificity, a practice which possibly annuls their benefit.