Identification of two anti- Candida antibodies associated with the survival of patients with candidemia.
Carla BromuroBrunella PosteraroRita MurriMassimo FantoniMario TumbarelloSanguinetti MaurizioRosanna DattiloRoberto CaudaAntonio CassoneAntonella TorosantucciPublished in: mBio (2023)
antigens. In particular, the patients with high titers of IgG reactive with two immunodominant, virulence-associated antigens (Als3 and MP65) had a higher 30-day survival. If confirmed by controlled, prospective clinical studies, our data could inform the development of antibody therapy to better treat a severe fungal infection such as candidiasis.