Nasal shedding of vaccine viruses after immunization with a Russian-backbone live attenuated influenza vaccine in India.
Lalit DarAnand KrishnanRamesh KumarShivram DhakadAvinash ChoudekarSumedha BaggaAmrit SharmaAmit KumarJyoti JethaniSiddhartha SahaRitvik AmarchandRakesh KumarAashish ChoudharyVenkatesh Vinayak NarayanGiridara GopalKathryn E LafondStephen LindstromPublished in: Influenza and other respiratory viruses (2023)
At day 2 post-vaccination in year 1, two-thirds of LAIV recipients were shedding vaccine viruses. Shedding of vaccine viruses varied between strains and was lower in year 2. More research is needed to determine the reason for lower virus shedding and vaccine efficacy for LAIV-A(H1N1)pdm09.