MGMT gene promoter methylation by pyrosequencing method correlates volumetric response and neurological status in IDH wild-type glioblastomas.

Tomohiro HosoyaMasamichi TakahashiMai Honda-KitaharaYasuji MiyakitaMakoto OhnoShunsuke YanagisawaTakaki OmuraDaisuke KawauchiYukie TamuraMiyu KikuchiTomoyuki NakanoAkihiko YoshidaHiroshi IgakiYuko MatsushitaKoichi IchimuraYoshitaka Narita

Published in: Journal of neuro-oncology (2022)

Evaluation of MGMTpm% by pyrosequencing is important in predicting the volumetric response and prognosis of glioblastoma patients with residual tumors.

Keyphrases

wild type
dna methylation
genome wide
gene expression
transcription factor
low grade
copy number
blood brain barrier
cerebral ischemia
subarachnoid hemorrhage