Genetic susceptibility in pneumoconiosis in China: a systematic review.

Sek Ying ChairJudy Yuet-Wa ChanBernard Man Hin LawMary Miu Yee WayeWai Tong Chien

Published in: International archives of occupational and environmental health (2022)

This review summarised the evidence demonstrating the association between genetic polymorphisms and pneumoconiosis susceptibility among people in China, and that various genotypes could modify their risk to develop pneumoconiosis. The findings prompt that identification of individuals at high pneumoconiosis risk through genetic screening and strategies limiting their exposure to dust could be a potential strategy for the control of this occupational disease in China.

Keyphrases

genome wide
copy number
gene expression
risk assessment