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Identification of Clinically Relevant Brain Endothelial Cell Biomarkers in Plasma.

Jenifer CordonMichael R DugganGabriela T GomezKrishna A PuchaZhongsheng PengHeather E DarkChristos DavatzikosGuray ErusAlexandria LewisAbhay R MoghekarJulián CandiaLuigi FerruciDimitrios KapogiannisKeenan A Walker
Published in: Stroke (2023)
In addition to identifying BEC proteins in plasma that relate to cerebral small vessel disease and dementia risk, we developed a composite score of plasma BEC proteins that may be used to estimate blood-brain barrier integrity and risk for adverse neurovascular outcomes.
Keyphrases
  • blood brain barrier
  • cerebral ischemia
  • endothelial cells
  • mild cognitive impairment
  • subarachnoid hemorrhage
  • white matter
  • type diabetes
  • adipose tissue
  • brain injury
  • insulin resistance
  • resting state