Identification of Clinically Relevant Brain Endothelial Cell Biomarkers in Plasma.
Jenifer CordonMichael R DugganGabriela T GomezKrishna A PuchaZhongsheng PengHeather E DarkChristos DavatzikosGuray ErusAlexandria LewisAbhay R MoghekarJulián CandiaLuigi FerruciDimitrios KapogiannisKeenan A WalkerPublished in: Stroke (2023)
In addition to identifying BEC proteins in plasma that relate to cerebral small vessel disease and dementia risk, we developed a composite score of plasma BEC proteins that may be used to estimate blood-brain barrier integrity and risk for adverse neurovascular outcomes.