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Unsuspected clonal spread of Methicillin-resistant Staphylococcus aureus causing bloodstream infections in hospitalized adults detected using whole genome sequencing.

Brooke M TalbotNatasia F JackoRobert A PetitDavid A PeguesMargot J ShumakerTimothy D ReadMichael Z David
Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Multiple clusters of closely related MRSA isolates can be identified using WGS among strains cultured from BSI in two hospitals. Genomic clustering of these infections suggest that transmission resulted from a mix of community spread and healthcare exposures long before BSI diagnosis.
Keyphrases
  • methicillin resistant staphylococcus aureus
  • healthcare
  • staphylococcus aureus
  • escherichia coli
  • air pollution
  • endothelial cells
  • mental health
  • single cell
  • copy number
  • genetic diversity
  • affordable care act