tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer.
Dongping MoXun TangYuyan MaDayu ChenWeiguo XuNing JiangJunyu ZhengFeng YanPublished in: Journal of translational medicine (2024)
3'tRF-AlaAGC might modulate macrophage polarization via binding to TRADD and increase the effect of M2 on promoting the chemoresistance in BC cells through NF-κb signaling pathway.
Keyphrases
- signaling pathway
- induced apoptosis
- pi k akt
- cell cycle arrest
- oxidative stress
- single cell
- epithelial mesenchymal transition
- endoplasmic reticulum stress
- cell therapy
- lps induced
- cancer stem cells
- cell proliferation
- immune response
- bone marrow
- cell death
- mesenchymal stem cells
- inflammatory response
- childhood cancer