Mito-TEMPO mitigates 5-fluorouracil-induced intestinal injury via attenuating mitochondrial oxidative stress, inflammation, and apoptosis: an in vivo study.

Prasad Kisan Tambe H S Qsee Sanjay Bharati

Published in: Inflammopharmacology (2023)

Mito-TEMPO exerted significant protective effect against 5-FU-induced intestinal toxicity. Therefore, it may be used as an adjuvant in 5-FU chemotherapy.

Keyphrases

oxidative stress
diabetic rats
high glucose
ischemia reperfusion injury
induced apoptosis
dna damage
early stage
drug induced
endothelial cells
locally advanced
radiation induced