Upadacitinib Induction and Maintenance Therapy Improves Abdominal Pain, Bowel Urgency, and Fatigue in Patients With Ulcerative Colitis: A Post Hoc Analysis of Phase 3 Data.

Silvio DaneseJacinda TranGeert D'HaensDavid T RubinNobuo AoyamaWen ZhouDapo IloXuan YaoYuri Sanchez GonzalezRemo Panaccione

Published in: Inflammatory bowel diseases (2023)

The findings of this study support the additional benefit of upadacitinib in treating moderately to severely active ulcerative colitis by demonstrating a statistically significant impact on clinically meaningful symptoms of fatigue, bowel urgency, and abdominal pain. (U-ACHIEVE induction and maintenance studies; NCT02819635; U-ACCOMPLISH induction study; NCT03653026).

Keyphrases

abdominal pain
ulcerative colitis
sleep quality
stem cells
machine learning
urinary incontinence
deep learning
case control
data analysis