Obesity in early onset breast cancer in African American patients.
Ida MicailyHannah HackbartMeghan ButrynMaysa M Abu-KhalafPublished in: The breast journal (2021)
Obesity is a modifiable risk factor in breast cancer patients and is predictive of disease outcomes in early-onset breast cancer survivors. The purpose of this review is to summarize the current evidence in the association between early-onset breast cancer and obesity, specifically in African-American women. Reviewing the molecular mechanisms and social determinants of disease in this population can provide a foundation for future interventions in prevention, detection, and treatment aiming at improving outcomes for young breast cancer patients.
Keyphrases
- early onset
- african american
- late onset
- insulin resistance
- weight loss
- metabolic syndrome
- high fat diet induced
- type diabetes
- weight gain
- end stage renal disease
- polycystic ovary syndrome
- chronic kidney disease
- newly diagnosed
- risk factors
- ejection fraction
- peritoneal dialysis
- skeletal muscle
- young adults
- glycemic control
- middle aged
- combination therapy
- patient reported