Towards a validated definition of the clinical transition to secondary progressive multiple sclerosis: A study from the Italian MS Register.
Pietro IaffaldanoGiuseppe LucisanoTommaso GuerraFrancesco PattiMarco OnofrjVincenzo Brescia MorraMauro ZaffaroniCarlo PozzilliEleonora CoccoPatrizia SolaGiuseppe SalemiMatilde IngleseRoberto BergamaschiClaudio GasperiniAntonella ConteMarco SalvettiGiacomo LusGiorgia Teresa ManiscalcoRocco TotaroMarika VianelloFranco GranellaElisabetta FerraroUmberto AgugliaMaurizia GattoFrancesca SangalliClara Grazia ChisariGiovanna De LucaAntonio CarotenutoDamiano BaronciniDelia ColomboMihaela NicaDamiano PaolicelliGiancarlo ComiMassimo FilippiMaria Pia AmatoMaria TrojanoPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)
Data-driven definitions demonstrated greater ability to capture SP transition than neurologist's definition and the global accuracy of DDA seems to be higher than the EXPAND definition.