Whole exome sequencing analyses reveal gene-microbiota interactions in the context of IBD.
Shixian HuArnau Vich VilaRanko GacesaValerie CollijChristine StevensJack M FuIsaac WongMichael E TalkowskiManuel A RivasFloris ImhannLaura BolteHendrik van DullemenGerard DijkstraMarijn C VisschedijkEleonora A FestenRamnik J XavierJingyuan FuMark J DalyCisca WijmengaAlexandra ZhernakovaAlexander KurilshikovRinse K WeersmaPublished in: Gut (2020)
This study highlights that both common and rare genetic variants affecting the immune system are key factors in shaping the gut microbiota in the context of IBD and pinpoints towards potential mechanisms for disease treatment.