Lagerstroemia indica extract regulates human hair dermal papilla cell growth and degeneration via modulation of β-catenin, Stat6, and TGF-β signaling pathway.

We suggest that L. indica extract prevents hair loss as well as stimulate hair growth by regulating the Wnt-β-catenin, JAK3-STAT6, and TGF-β1-Smad signaling pathways, and may be further developed as a novel functional cosmetic for preventing hair loss.