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TET2-mediated DNA hydroxymethylation of TGFB1 is related to selective intrauterine growth restriction in monochorionic twin pregnancies.
Jiayi Jiang
Dianjie Li
Yixiang Zhong
Yi Zhang
Mei Zhong
Published in:
Placenta (2023)
We elucidated the functional roles of TET2 and DNA hydroxymethylation in trophoblasts and identified a novel DNA regulatory mechanism, providing a basis for further exploration of DNA epigenetic regulatory patterns in sIUGR.
Keyphrases
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circulating tumor
cell free
single molecule
transcription factor
nucleic acid
gene expression
dna methylation
circulating tumor cells
preterm birth
pregnant women