Quantitative analysis of Gd in the protein content of the brain following single injection of gadolinium-based contrast agents (GBCAs) by size exclusion chromatography.
Achmad Adhipatria Perayabangsa KartamihardjaHirofumi HanaokaPutri AndrianaSatomi KameoAyako TakahashiHiroshi KoyamaYoshito TsushimaPublished in: The British journal of radiology (2019)
Intact GBCA are able to penetrate a series of brain barrier immediately after administration regardless the type of the chelate. Gd may be bound with macromolecules that may cause Gd retention in the brain.