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Integrating single-cell and spatial transcriptomics reveals endoplasmic reticulum stress-related CAF subpopulations associated with chordoma progression.

Tao-Lan ZhangChao XiaBo-Wen ZhengHai-Hong HuLing-Xiang JiangDavid EscobarBo-Yv ZhengTian-Dong ChenJing LiGuo-Hua LvWei HuangYi-Guo YanMing-Xiang Zou
Published in: Neuro-oncology (2023)
These findings depict the CAF landscape for chordoma and may provide insights into the development of novel treatment approaches.
Keyphrases
  • single cell
  • endoplasmic reticulum stress
  • rna seq
  • induced apoptosis
  • high throughput
  • oxidative stress
  • combination therapy
  • smoking cessation