Hypofractionated radiotherapy for glioblastoma: A large institutional retrospective assessment of 2 approaches.

Thomas H BeckhamMichael K RooneyMary F McAleerAmol J GhiaMartin C TomSubha PerniSusan McGovernDavid GrosshansCaroline ChungChenyang WangBrain DeTodd SwansonArnold PaulinoWen JiangSherise FergusonChirag B PatelJing LiDebra N Yeboa

Published in: Neuro-oncology practice (2024)

This study demonstrates comparable survival outcomes between 3w-RT and 4w-RT regimens in GBM patients. Receipt and timing of TMZ were strongly associated with survival outcomes. The potential benefit of dose-escalated hypofractionation for patients not receiving chemotherapy warrants further investigation and emphasizes the importance of personalized treatment approaches.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
radiation therapy
prognostic factors
early stage
squamous cell carcinoma
small cell lung cancer
risk assessment
radiation induced
combination therapy