Antiseizure medication use during pregnancy and risk of ASD and ADHD in children.

Kelsey Kathleen Wiggs Martin E Rickert Ayesha C SujanPatrick D QuinnHenrik LarssonPaul Lichtenstein Anna Sara Oberg Brian M D'Onofrio

Published in: Neurology (2020)

We found no evidence of risk related to exposure to lamotrigine, whereas we observed elevated risk of ASD and ADHD related to maternal use of valproic acid. Associations with carbamazepine were weak and not statistically significant. Our findings add to a growing body of evidence that suggests that certain ASMs may be safer than others in pregnancy.

Keyphrases

attention deficit hyperactivity disorder
autism spectrum disorder
working memory
young adults
physical activity