Evaluation of Anticancer Efficacy of D-α-Tocopheryl Polyethylene-Glycol Succinate and Soluplus ® Mixed Micelles Loaded with Olaparib and Rapamycin Against Ovarian Cancer.

Yu Been ShinJu-Yeon ChoiMoon Sup YoonMyeong Kyun YooDae Hwan ShinJeong-Won Lee

Published in: International journal of nanomedicine (2024)

Compared to the control, OLA/RAPA-TPGS/SOL showed significant tumor inhibition. These findings lay a foundation for the use of TPGS/SOL mixed micelles loaded with OLA and RAPA in the treatment of ovarian cancer.

Keyphrases

drug delivery
cancer therapy
drug release
combination therapy